In a highly anticipated match-up between two top contenders, Arsenal will face off against City in an early season showdown.
De Bruyne is a doubt after being forced out at halftime of their Champions League stalemate with Inter Milan in midweek.
However, Guardiola was refusing to write him off on Friday.
He said, “He feels a little better today... Tomorrow we train and we will see. He could be (involved) ..."